Learn How to Pronounce felodipine
(Listen to the audio above for the stress and intonation)
The Expert's Take

Meaning and Context
Felodipine is a dihydropyridine-class calcium channel blocker (CCB) prescribed primarily for the management of hypertension, or high blood pressure. Approved by the FDA, this vasodilator medication functions by selectively inhibiting the influx of calcium ions into vascular smooth muscle cells, resulting in the relaxation and widening of peripheral arteries. This pharmacological action reduces systemic vascular resistance, thereby effectively lowering blood pressure and decreasing the workload on the heart. As a key pharmaceutical agent in cardiovascular therapy, felodipine is instrumental in mitigating the risk of associated complications such as stroke, heart attack, and kidney disease. It is commercially available under the brand name Plendil, as well as in various generic formulations, and is often considered a first-line treatment option within clinical guidelines for hypertension management. Patients typically take this oral medication once daily, and its efficacy is frequently monitored alongside lifestyle modifications like diet and exercise.
Common Mistakes and Alternative Spellings
The standard and correct spelling is felodipine. Common misspellings and typographical errors often arise from phonetic misinterpretation or keyboard slips. Frequent variations include "felodopine," substituting the 'i' with an 'o', and "felodipin," omitting the final 'e'. Other errors are "flodipine," swapping the 'e' for an 'o' in the first syllable, and "felodpine," dropping the second 'i'. The "fe-" prefix is sometimes mistakenly written as "ph-" in errors like "phelodipine," likely due to the 'f' sound being associated with the 'ph' digraph in other medical terms. Care should also be taken not to confuse it with other similar-sounding calcium channel blockers, such as amlodipine or nifedipine, when writing or transcribing the drug name.
Example Sentences
After his diagnosis of stage 2 hypertension, his cardiologist initiated treatment with a low dose of felodipine to help safely lower his blood pressure.
The pharmacy dispensed the generic version of felodipine, which provided the same therapeutic benefit as the brand-name Plendil at a reduced cost.
A common side effect of felodipine is peripheral edema, or swelling in the ankles, which the patient reported at her follow-up appointment.
Because felodipine can cause reflex tachycardia, it is sometimes prescribed in combination with a beta-blocker for a more balanced cardiovascular effect.
The clinical study demonstrated that felodipine was particularly effective in treating isolated systolic hypertension in elderly patients.
Patients are advised to avoid grapefruit and grapefruit juice while taking felodipine, as it can interfere with the drug's metabolism and lead to potentially dangerous increases in its concentration in the bloodstream.
Sources and References
For the medication "felodipine," I used highly authoritative medical sources. I reviewed the patient and professional monographs on Drugs.com, which often include phonetic spellings. I also checked its entries on the OED and Wiktionary for standard dictionary pronunciations. To hear it spoken clearly, I listened to the audio recording on Forvo. The Wikipedia article served as a secondary reference for its phonetic transcription.
- https://en.wiktionary.org/wiki/felodipine
- https://en.wikipedia.org/wiki/Felodipine
- https://forvo.com/word/felodipine/
- https://www.drugs.com/mtm/felodipine.html
- https://www.drugs.com/monograph/felodipine.html
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